- All characters from Resident Evil 4 and 5 Mercenaries modes are playable
- This includes Leon, Ada, Krauser, HUNK, Wesker, Chris, Jill, Sheva
- Eight Mercenaries stages from Resident Evil 5 and the four Mercenaries stages from Resident Evil 4
- There will be hidden characters who have not previously been in Mercenaries
- New game modes
- Alternate costumes for characters
- Resident Evil 4 stages may have been made more like the Resident Evil 5 Mercenaries stages (different time crystals, more enemies, graphical face-lifts)